CONSERVATION: Scientists are trying to turn stem cells into sperm and eggs cells in an attempt to save critically endangered species

Northern white rhino image via Wikipedia

Due to poaching, the northern white rhino (Ceratotherium simum cottoni) is on the brink of extinction. Today, it’s thought that there are fewer than five northern white rhinos remaining worldwide. However, scientists are trying to use stem cells to save this remarkable animal. More via New Scientist:

For the first time researchers have turned frozen skin cells from two highly endangered species – the northern white rhino and the baboon-like drill – into stem cells that can become any cell in the body, including sperm and eggs. These could be used to impregnate animals through techniques similar to in vitro fertilisation (IVF).

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Loring’s work is made possible by a menagerie on ice called The Frozen Zoo, a collection of skin cells from more than 8600 animals representing around 800 species at the San Diego Zoo Institute for Conservation Research, California.

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Using viruses, the researchers introduced four genes that are highly expressed in human embryonic stem cells into the skin cells. This reverted the animals’ skin cells to their embryonic state. A few weeks later the researchers had colonies of induced pluripotent stem cells (iPSCs) for both drills and rhinos.

The researchers now hope to turn the drill iPSCs into sperm cells and the rhino iPSCs into egg cells, which could help preserve the species through techniques similar to IVF. They wouldn’t need a living drill or northern white rhino to carry the pregnancy – another primate could be a surrogate mother for a drill embryo, for instance.

Continue reading this article at New Scientist

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